Commonly described dissolution methods are product-dependent. Therefore, it is not possible to know whether the observed dissolution characteristics are a reflection of the product (formulation and/or manufacturing) attributes or because of the experimental conditions (apparatus, rpm, medium, etc.) employed.
For an appropriate and accurate assessment of dissolution characteristics of a product, the dissolution method must be product-independent. The use of crescent shape spindle has been suggested based on this principle, thus providing true product dissolution characteristics. Please see the following links for further discussion:https://bioanalyticx.com/simpler-and-more-appropriate-dissolution-testing/
(2) http://www.drug-dissolution-testing.com/blog/files/Flyer.pdf
(3) https://bioanalyticx.com/product-dependent-dissolution-testing-a-scientifically-invalid-practice/
(4)