Considering the flaws of poor hydrodynamics of the most commonly used apparatuses, paddle and basket, it is very well established that these apparatuses are not qualified and validated to provide relevant and reproducible dissolution results. Therefore, it is natural that people are seeking alternatives. The vessel-based apparatuses using the crescent shape spindle provides such an alternative. The next obvious question would be, are such apparatuses qualified to be used as dissolution testers? Also, have these been standardized? The answer to both questions is yes, as explained below. please click here for complete article