A drug dissolution test is one of the most critical and important tests used for developing and evaluating tablet/capsule products. However, unfortunately, as conducted at present, the test is also perhaps one of the most frustrating and the least value-adding tests one would use. The test is often promoted as a quality control test or tool as well, however, without defining or linking to a quality parameter/end-point. It is conducted using apparatuses that have never been validated for the intended purpose or objective, further increasing frustration. This article describes reasons for such practices and frustrations and suggests a simple approach to address the issues and concerns.
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