Often I visit the PubMed site (link) to search for recent articles with the search phrase “drug dissolution.” A chart on the top right corner of the search outcome shows the number of articles published yearly for the search phrase. I have reproduced (below) this chart from 1970 to 2019. As seen from the chart, there is a dramatic decrease in the number of publications during 2019. This might not be a scientific or statistical conclusion; however, the decrease (about 27%) is significant.
There is a strong possibility that scientists have lost credibility and faith in the relevancy of drug dissolution testing. I was highlighting for the past years through my citizen petition to the FDA in 2018 (link). In the future, people should take note of this observation and use caution in conducting dissolution tests using USP testers and methods.